PHARMACEUTICAL COMPOSITIONS

摘要

The invention relates to a pharmaceutical composition for the slow release o f an active agent in the gastrointestinal tract, comprising several particles which contain an active agent and which are coated with a material that is insoluble in gastrointestinal juice. The particles have a core consisting of a homogenous mixture comprising a pharmaceutical active agent and a polymer which is insoluble in gastrointestinal juice, with a maximum average inner pore diameter of 35 .mu.m. The inventive composition enables an efficient release which is independent of pH, even with comparatively small quantities of polymer. It is characterised by good storage resistance and in particular , is also suitable for non-spherical particles.