发明名称 |
METHODS AND COMPOSITIONS FOR INHIBITING, PREVENTING, OR REDUCING TUMOR CELL GROWTH IN PATIENTS RESISTANT TO THE ANTINEOPLASTIC EFFECTS OF ANTIESTROGEN THERAPY |
摘要 |
<p>Methods and kits for diagnosing tumorigenicity and for determining whether a cancer patient is resistant to the pharmacological effects of antiestrogen therapy. Increased levels of the PCDGF (GP88) growth factor are indicative of tumorigenicity and resistance to the pharmacological effects of antiestrogen therapy. The methods and kits of the invention are useful for assessing the tumorigencity of a biological sample from a patient and determining whether the patient is a candidate for antiestrogen, including tamoxifen, therapy.</p> |
申请公布号 |
EP1404365(B1) |
申请公布日期 |
2011.01.26 |
申请号 |
EP20020739838 |
申请日期 |
2002.06.14 |
申请人 |
A & G PHARMACEUTICALS, INC. |
发明人 |
SERRERO, GINETTE |
分类号 |
A61K39/395;A61K45/00;A61K31/138;A61K38/00;A61K39/00;A61K39/38;A61K48/00;A61P35/00;A61P43/00;C07K14/475;C07K16/22;C07K16/30;C12N15/09;C12Q1/02;C12Q1/68;G01N33/574;G01N37/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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