发明名称 NMDA RECEPTOR AGONIST PHARMACEUTICAL COMPOSITIONS
摘要 This invention relates to stable pharmaceutical compositions of the NMDA receptor agonist, (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol], methods of preparing such pharmaceutical compositions and methods of treating stroke, spinal cord trauma, traumatic brain injury, multiinfarct dementia, CNS degenerative diseases such as Alzheimer's disease, senile dementia of the Alzheimer's type, Huntington's disease, Parkinson's disease, epilepsy, amyotrophic lateral sclerosis, pain, AIDS dementia, psychotic conditions, drug addictions, migraine, hypoglycemia, anxiolytic conditions, urinary incontinence and an ischemic event arising from CNS surgery, open heart surgery or any procedure during which the function of the cardiovascular system is compromised using the pharmaceutical compositions.
申请公布号 PL362080(A1) 申请公布日期 2004.10.18
申请号 PL20010362080 申请日期 2001.12.05
申请人 PFIZER PRODUCTS INC. 发明人 HONG JINYANG;KIM YESOOK
分类号 C07D211/52;A61K9/00;A61K31/445;A61K31/675;A61K47/02;A61K47/12;A61K47/18;A61P3/08;A61P9/02;A61P9/10;A61P13/02;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/28 主分类号 C07D211/52
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