发明名称 |
Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
摘要 |
The present invention provides peptide analogues which are antagonists of gastric inhibitory peptide (GIP). The peptides, based on GIP 1-42 include substitutions and/or modifications which have enhanced resistance to degradation by the enzyme dipeptidyl peptidase IV (DPP IV). The invention also provides a process of N terminally modifying GIP and the use of the peptide analogues for treatment of diabetes.
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申请公布号 |
US7875587(B2) |
申请公布日期 |
2011.01.25 |
申请号 |
US20070713892 |
申请日期 |
2007.03.05 |
申请人 |
UUTECH LIMITED |
发明人 |
GAULT VICTOR A.;O'HARTE FINBARR PAUL MARY;IRWIN NIGEL;FLATT PETER RAYMOND |
分类号 |
A61K38/10;A61K38/00;A61K38/22;C07K14/575 |
主分类号 |
A61K38/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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