| 摘要 |
The present invention is related to a process for the preparation of a pellet mass, wherein the premix containing one pharmaceutically active ingredient(s) is homogenized to obtain a starting powder mixture; spraying a granulating liquid onto said powder mixture; spheronizing, drying and fractionating thus obtained particles, wherein the starting or partially pelletized powder mixture is blended with seeding pellets having identical or essentially similar composition but smaller average particle size than the particle size of the desired product traction of the pellets. |
