| 发明名称 |
Folate mimetics and folate-receptor binding conjugates thereof |
| 摘要 |
A cell population expressing folate receptors is selectively targeted with a non-peptide folic acid analogue. The non-peptide folic acid analogue is conjugated to a diagnostic or therapeutic agent to enable selective delivery of the agent to the targeted cell population.
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| 申请公布号 |
US7875612(B2) |
申请公布日期 |
2011.01.25 |
| 申请号 |
US20040475876 |
申请日期 |
2004.06.21 |
| 申请人 |
PURDUE RESEARCH FOUNDATION;ENDOCYTE, INC. |
发明人 |
GREEN MARK A.;KE CHUN-YEN;LEAMON CHRISTOPHER P. |
| 分类号 |
A01N43/64;A01N43/58;A01N43/60;A01N43/90;A61K31/495;A61K31/50;A61K31/519;A61K31/53;A61K51/04;C07D253/08;C07D475/00;C07D475/04;C07D487/00 |
主分类号 |
A01N43/64 |
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