发明名称 Annelated pyrrole compounds as gastric proton pump inhibitors for treating ulcer
摘要 Use of [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid of the formula (la), a physiologically acceptable salt or a physiologically hydrolysable ester thereof, in the preparation of a pharmaceutical composition for inhibiting a gastric proton pump, for reducing the sensitivity of gastric mucosa to topical injury or for treating or preventing gastric acid-related conditions is disclosed. These pharmaceutical compositions comprising the compound of formula (la) are suitable for treating or preventing gastric mucosal lesions, erosive gastritis, non-erosive gastritis, gastric ulceration, Ulcus duodeni or Ulcus ventriculi.
申请公布号 NZ536444(A) 申请公布日期 2006.12.22
申请号 NZ20030536444 申请日期 2003.05.16
申请人 MERCKLE GMBH 发明人 SMOLKA, ADAMS J;HAMMOND, CHARLES E;GUPTA, SANDEEP
分类号 A61K31/403;A61P1/04;C07D 主分类号 A61K31/403
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