METODO PARA LA PREPARACION A BAJA TEMPERATURA DE PIEZAS DE BIOCERAMICAS CON POROSIDAD TRIDIMENSIONAL DISENADA E INTERCONECTADA

摘要

Method for the low-temperature preparation of bioceramic parts with patterned and interconnected three-dimensional porosity. The method is based on the gelification of an aqueous suspension of a ceramic material and a biocompatible bonding agent inside a mould. The method allows the introduction, during the manufacturing process, of biological or pharmacologically active substances. The mould pattern determines essentially the porosity of the part. The size of the pore, the geometry and the degree of porosity may be modified in the three spatial directions. The size of the pore which can be achieved as well as the fact that the pores are interconnected facilitates the vascularization process, the integration of the implanted material and, in most cases, the subsequent regeneration of the tissue. The ultimate aim of these parts is the application thereof as implants for regeneration of the bone tissue in tissue engineering.