AGLYCOSYL ANTI-CD154(CD40 LIGAND) ANTIBODIES AND USES THEREOF
摘要
<p>The invention relates to aglycosyl anti-CD154 antibodies or antibody derivatives, characterized by a modification at the conserved N-linked site in the C H2 domains of the Fc portion of said antibody. The invention also relates to the treatment of immune response related diseases and inhibition of unwanted immune response with such aglycosylated anti-CD154 antibodies or antibody derivatives thereof.</p>
申请公布号
HK1090064(A1)
申请公布日期
2011.01.21
申请号
HK20060110452
申请日期
2006.09.20
申请人
BIOGEN IDEC MA INC.
发明人
TAYLOR, FREDERICK, R.;BENJAMIN, CHRISTOPHER, D.;BURKLY, LINDA, C.;GARBER, ELLEN, A.