发明名称 Methods For Identifying Cells Suitable For Large-Scale Production of Recombinant Proteins
摘要 The present invention provides methods of identifying a clonal population of cells suitable for large-scale production of a protein of interest. The invention further provides methods for high-throughput screening for genetic rearrangements in the gene encoding the protein of interest, whereby the absence of a deletion in the gene encoding the protein of interest indicates that the cell is suitable for large-scale production of the protein of interest.
申请公布号 US2011014624(A1) 申请公布日期 2011.01.20
申请号 US20090921717 申请日期 2009.03.12
申请人 WYETH LLC 发明人 MCCARTHY KEVIN MICHAEL;HONE MEGAN JILL;HELLER-HARRISON ROBIN ALLISON;LEONARD MARK WILLIAM
分类号 C12Q1/68;C12N5/071 主分类号 C12Q1/68
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