发明名称 COMBINATION OF A HUMAN INTERLEUKIN-6 ANTAGONIST AND A HUMAN INTERLEUKIN-6 RECEPTOR ANTAGONIST IN THERAPY OF TUMOUR DISEASES
摘要 The prevent invention provides the use of a combination of an anti-human interleukin-6 monoclonal antibody (IL-6A) and an anti-human IL-6 receptor monoclonal antibody (IL-6RA) as effective components: (1) in the treatment of tumours produce Interleukin-10 which is induced by Interleukin-6, (2) in the treatment of multiple myeloma (plasmozytoma) produces Interleukin-10 which is induced by Interleukin-6 and (3) in the treatment of Interleukin-6 dependent tumours. Interleukin-10 leads to an enhanced proliferation of tumour cells.
申请公布号 WO2011006273(A1) 申请公布日期 2011.01.20
申请号 WO2010CH00183 申请日期 2010.07.14
申请人 KOVACS-BENKE, EVA 发明人 KOVACS-BENKE, EVA
分类号 C07K16/24;A61P35/00;C07K16/28 主分类号 C07K16/24
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