发明名称 |
Cancer diagnosis and treatment using anti-ROBO1 antibody |
摘要 |
A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROB01 protein is disclosed. |
申请公布号 |
AU2005227598(B2) |
申请公布日期 |
2011.01.20 |
申请号 |
AU20050227598 |
申请日期 |
2005.03.31 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;HIROYUKI ABURATANI |
发明人 |
SHIN-ICHI FUNAHASHI;MASASHI FUKAYAMA;HIROTAKA ITO;YASUKO KINOSHITA;AKIRA WATANABE;YUKIO ITO;MASAHIRO ARAI;HIROYUKI ABURATANI;TOSHIHIKO OHTOMO;YOSHITAKA HIPPO |
分类号 |
C07K16/30;C12N15/02;C12N15/09;G01N33/574;G01N33/576 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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