发明名称 |
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 GENE |
摘要 |
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the Eg5 gene (Eg5 gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of the Eg5 gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Eg5 expression and the expression of the Eg5 gene using the pharmaceutical composition; and methods for inhibiting the expression of the Eg5 gene in a cell.
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申请公布号 |
US2011015250(A1) |
申请公布日期 |
2011.01.20 |
申请号 |
US20100754110 |
申请日期 |
2010.04.05 |
申请人 |
BUMCROT DAVID;TAN PAMELA;VORNLOCHER HANS-PETER;GEICK ANKE |
发明人 |
BUMCROT DAVID;TAN PAMELA;VORNLOCHER HANS-PETER;GEICK ANKE |
分类号 |
A61K31/713;A61P35/00;C07H21/02;C12N5/071;C12N15/63 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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