COMPLIANT MICROFLUIDIC SAMPLE PROCESSING DISKS.

摘要

Microfluidic sample processing disks with a plurality of fluid structures formed therein are disclosed. Each of the fluid structures preferably includes an input well (20) and one or more process chambers (30) connected to the input well (20) by one or more delivery channels (42, 44, 46). The process chambers (30) may be arranged in a compliant annular processing ring that is adapted to conform to the shape of an underlying thermal transfer surface under pressure. That compliance may be delivered in the disks of the present invention by locating the process chambers in an annular processing ring in which a majority of the volume is occupied by the process chambers. Compliance within the annular processing ring may alternatively be provided by a composite structure within the annular processing ring that includes covers attached to a body using pressure sensitive adhesive.