USE OF COMPOUNDS DERIVED FROM BIS-BENZAMIDINES AS FLUOROGENIC AGENTS FOR SIGNALLING SPECIFIC SEQUENCECS OF DOUBLE-STRAND DNA, AND NOVEL COMPOUNDS
摘要
The invention relates to the use of compounds derived from bis-benzamidines as fluorogenic agents for signalling specific sequences of double-strand DNA and to novel compounds. More specifically, the invention relates to the use of compounds derived from propamidine-pentamidine and containing 4-aminobenzamidine groups as fluorogenic DNA-sequence-recognition agents since they can bind to the DNA minor groove, and to novel compounds.
申请公布号
WO2011007038(A2)
申请公布日期
2011.01.20
申请号
WO2010ES70486
申请日期
2010.07.13
申请人
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA;VAZQUEZ, OLALLA;ISIDRO LOPEZ, MATEO;VAZQUEZ SENTIS, EUGENIO;MASCARENAS, JOSE LUIS
发明人
VAZQUEZ, OLALLA;ISIDRO LOPEZ, MATEO;VAZQUEZ SENTIS, EUGENIO;MASCARENAS, JOSE LUIS