METHOD TO FORECAST RESISTANCE OF MEMBRANES OF PERIPHERAL BLOOD ERYTHROCYTES IN CASE OF EXACERBATION OF HERPES-VIRUS INFECTION IN EXPECTING MOTHERS

摘要

FIELD: medicine. ^ SUBSTANCE: invention relates to the field of medicine. To forecast resistance of membranes of erythrocytes of peripheral blood in case of exacerbation of herpes-virus infection in expecting mothers, content of lysophosphatidyl choline is determined on silica gel with the help of 2D thin-layer chromatography in phospholipid composition of membranes. Simultaneously, in the same portion of blood in membranes of erythrocytes by method of disk electrophoresis, content of protein of band 4.1 is identified in staged gradient polyacrylamide 10% gel with dodecyl sodium sulfate. Integral assessment of interconnection between examined parametres in healthy expecting mothers and expecting mothers who suffered exacerbation of herpes-virus infection is carried out through determination of discriminant function (D) with the help of discriminant equation according to the formula: D=-6.790 x band 4.1 + {+0.609ùLph}. If D value equals to or is less than -19.01, non-resistance of erythrocytes membranes is forecasted. ^ EFFECT: method makes it possible to forecast resistance of membranes of erythrocytes of peripheral blood in case of exacerbation of herpes-virus infection of expecting mothers. ^ 1 tbl