| 发明名称 |
Mutant SREBP-1c promoters and use thereof |
| 摘要 |
<p>The present invention provides a novel fructose responsive transcription control cis-element and a transcriptional regulatory factor that interacts therewith, a non-human animal having them transferred or inactivated, a diagnostic method for genetic susceptibility to a metabolic disorder using them, and a screening method for a prophylactic or therapeutic drug for a metabolic disorder using them.</p> |
| 申请公布号 |
EP1600507(B1) |
申请公布日期 |
2011.01.19 |
| 申请号 |
EP20040712761 |
申请日期 |
2004.02.19 |
| 申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
NISHIO, YOSHIHIKO;MAEGAWA, HIROSHI;KASHIWAGI, ATSUNORI |
| 分类号 |
C12N15/09;A01K67/027;A61K38/00;A61K39/395;A61K45/00;A61P3/00;C07K14/47;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50;G01N33/68 |
主分类号 |
C12N15/09 |
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