发明名称 |
TAT DNA SEQUENCES, GENE CONSTRUCTS, VACCINE AND PROCESSES THEREOF |
摘要 |
The present invention relates to non toxic, immunogenic viral Tat DNA sequences comprising wherein the Tat Sequence is rendered non toxic and immunogenic by insertion of T-Helper Epitope into the Cysteine-rich domain, or Basic domain or Core domain of said Tat DNA sequence, optionally along with insertion of a synthetic Intron between C-terminal region and Exon II region of the Tat DNA Sequence. The present invention also relates to elongation factor promoter constructs and process thereof. Also the present invention relates to a process of obtaining the non toxic and immunogenic Tat DNA sequence and vaccine and a method thereof. |
申请公布号 |
EP2274427(A2) |
申请公布日期 |
2011.01.19 |
申请号 |
EP20090746294 |
申请日期 |
2009.05.14 |
申请人 |
JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH |
发明人 |
RANGA, UDAYKUMAR |
分类号 |
C12N15/48;A61K31/7088;A61P31/18 |
主分类号 |
C12N15/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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