| 发明名称 |
NUCLEIC ACID MOLECULES ENCODING TRANSMEMBRANE SERINE PROTEASES, THE ENCODED PROTEINS AND METHODS BASED THEREON |
| 摘要 |
Provided herein are polypeptides that include the protease domain of a type II transmembrane serine protease (MTSP) as a single chain. Methods using the polypeptides to identify compounds that modulate the protease activity of an MTSP are provided. Also provided are MTSPs designated MTSP3 and MTSP4 and a form of an MTSP designated MTSP6. |
| 申请公布号 |
EP1252300(B1) |
申请公布日期 |
2011.01.19 |
| 申请号 |
EP20010905377 |
申请日期 |
2001.02.02 |
| 申请人 |
DENDREON CORPORATION |
发明人 |
MADISON, EDWIN, L.;ONG, EDGAR, O.;YEH, JIUNN-CHERN |
| 分类号 |
A01K67/027;C12N9/64;A61K38/48;A61K39/395;A61K45/00;A61K48/00;A61P9/14;A61P35/00;A61P35/04;A61P43/00;C07K16/40;C12M1/34;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/99;C12N15/09;C12P21/08;C12Q1/37;C12R1/19;C12R1/84;G01N33/15;G01N33/50;G01N33/53;G01N37/00 |
主分类号 |
A01K67/027 |
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