USE OF CYCLIC BIOISOSTERS DERIVATIVES OF PURINE SYSTEM FOR TREATMENT OF DISORDERS CAUSED BY ABNORMALITIES OF NITRERGIC AND dopaminergic systems

摘要

, (I), (II)The invention relates to compounds of general structural formula (I), wherein R = formula (II), Li, Na, K; R= -Н, -NH, -Вr, -Сl, -ОН, -СООН; В = -N=, CH=, Z = -СН=, -N=; A = -N at В = -N, Z = -СН-; А = -СН= at В = -N=; Z = -СН-; А = -СН= at В = -N=, Z - -N=; A-СН= at В = -СН=, Z = -СН=; А = -СН= at В = -СН=, Z = -N= and to the pharmacologically acceptable salts thereof used in the form of an active ingredient exhibiting an activity with respect to nitrergic and/or dopaminergic systems for pharmacological compounds in the form of a neuroprotector, for improving a cognitive function, normalising a psychophysiological state and for treating a large range of neuropsychic and cardiovascular diseases, and diseases caused by a substance abuse and by a hyperactive immune system of mammals including a human being.