发明名称 Spiro amino compounds suitable for the treatment of inter alia sleep disorders and drug addiction
摘要 <p>The invention concerns a spiro-amino compound of Formula (VI) wherein m is 1 or 2 or 3, n is 1 or 2, R is selected from a 5- or 6-membered aromatic ring and a 5-or 6-membered heteroaromatic ring comprising 1 to 3 heteroatoms selected from S, O e N, such ring being substituted with one or two substituents selected from the group consisting of (C 1 -C 3 )alkyl, (C 3 -C 5 )cycloalkyloxy, (C 1 -C 3 )alkylcarbonyl, phenyl optionally substituted with one or more halogen atoms, a 5- or 6-membered heterocycle comprising at least one nitrogen atom; P is a substituent Q or COQ, wherein Q is selected from the group consisting of phenyl, pyridil, pyrimidil, quinolyl, isoquinolyl, quinoxalyl, benzofuranyl, imidazotriazolyl, being such Q optionally substituted with one or more substituents selected from the group consisting of (C 1 -C 3 )alkyl, halogen, trifluoromethyl, carbammido, methylcarbammido, carboxy.</p>
申请公布号 EP2275421(A1) 申请公布日期 2011.01.19
申请号 EP20090425285 申请日期 2009.07.15
申请人 ROTTAPHARM S.P.A. 发明人 STASI, LUIGI PIERO;ROVATI, LUCIO
分类号 C07D401/12;A61K31/438;A61P25/30;C07D401/14;C07D417/06;C07D417/14 主分类号 C07D401/12
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