发明名称 METHOD FOR ASSESSMENT OF IMMUNOMODULATORS
摘要 FIELD: veterinary medicine. ^ SUBSTANCE: invention is related to veterinary immunology. Method includes introduction of investigated immunomodulator and assessment of immune status. At that PPD-tuberculin is injected to mammals subcutaneously in dose of 1.3-1.8 ml per animal. Then after 3-5 days immunomodulator is injected per 1 kg of animal weight in 0.2-1 ml physiological solution. After 7-10 days BCG vaccine is injected intracutaneously. After 30-35 days after immunisation virulent culture M. bovis is injected subcutaneously in dose of 0.0001 mg, and after 30-35 days postmortem study of slaughtered animals is carried out. Assessment of immune status is carried out by index of protection: from 100% to 67% - high capacity of immunomodulator, 66-43% - medium, from 42% - low. ^ EFFECT: method makes it possible to increase accuracy of assessment with reduction of material expenses. ^ 2 tbl, 2 ex
申请公布号 RU2354401(C1) 申请公布日期 2009.05.10
申请号 RU20070128669 申请日期 2007.07.25
申请人 GOSUDARSTVENNOE NAUCHNOE UCHREZHDENIE VSEROSSIJSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT BRUTSELLEZA I TUBERKULEZA ZHIVOTNYKH SO ROSSEL'KHOZAKADEMII (GNU VNIIBTZH SO RASKHN) 发明人 BAZHIN MIKHAIL ARISTOKLEVICH;VLASENKO VASILIJ SERGEEVICH;NOVIKOV ARTEM NIKOLAEVICH
分类号 A61D99/00;A61K39/04 主分类号 A61D99/00
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