发明名称 |
PEPTIDANTIKÖRPERDEPLETION UND ANWENDUNG ZUR PROBENVORBEREITUNG FÜR MASSENSPEKTROMETRIE |
摘要 |
The present invention relates, e.g., to a method for pre-processing a sample for mass spectral analysis, comprising cleaving proteins in the sample to peptides and immunodepleting highly abundant and/or well-ionizing and/or proteotypic peptides from the sample. Also described are methods for identifying well-ionizing peptides for use in this and other methods; analytic (diagnostic) methods using antibodies against highly ionizable peptides from a protein target of interest; and compositions kits and devices comprising antibodies of the invention. |
申请公布号 |
AT495447(T) |
申请公布日期 |
2011.01.15 |
申请号 |
AT20070810163T |
申请日期 |
2007.07.03 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
VAN EYK, JENNIFER;GRAHAM, DAVID;GUNDRY, REBEKAH |
分类号 |
G01N33/68;C07K16/00;G01N33/543 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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