HDAC 6 INHIBITOR-BASED METHODS FOR TREATING CANCER
摘要
This invention provides methods for treating a subject afflicted with cancer, comprising concurrently administering (i) an HDAC 6-selective inhibitor and (ii) a suitable cytotoxic agent such as SAHA, doxorubicin or etoposide. This invention also provides methods for inducing the death of a transformed cell such as a cancer cell, comprising concurrently contacting the cell with (i) an HDAC 6-selective inhibitor and (ii) a suitable cytotoxic agent such as SAHA, doxorubicin or etoposide.
申请公布号
WO2011005688(A1)
申请公布日期
2011.01.13
申请号
WO2010US40914
申请日期
2010.07.02
申请人
MEMORIAL SLOAN-KETTERING CANCER CENTER;MARKS, PAUL, A.;NAMDAR, MANDANA;XU, WEISHENG