发明名称 |
CANCEROUS DISEASE MODIFYING ANTIBODIES |
摘要 |
<p>The present invention relates to a method for producing cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.</p> |
申请公布号 |
WO2011004899(A1) |
申请公布日期 |
2011.01.13 |
申请号 |
WO2010JP61730 |
申请日期 |
2010.07.05 |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED;YOUNG, DAVID S.F.;FINDLAY, HELEN P.;HAHN, SUSAN E.;POPP, LISA A. |
发明人 |
YOUNG, DAVID S.F.;FINDLAY, HELEN P.;HAHN, SUSAN E.;POPP, LISA A. |
分类号 |
C07K16/30;A61P35/00;G01N33/574 |
主分类号 |
C07K16/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|