发明名称 BI-SPECIFIC DIGOXIGENIN BINDING ANTIBODIES
摘要 This invention relates to bispecific antibodies and antibody fragments against a target protein and a hapten, wherein the hapten is PEG or biotin, most preferably digoxigenin, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical 5 compositions containing said antibodies, and uses thereof.
申请公布号 CA2766608(A1) 申请公布日期 2011.01.13
申请号 CA20102766608 申请日期 2010.06.30
申请人 F. HOFFMANN-LA ROCHE AG 发明人 BRAMLAGE, BIRGIT;BRINKMANN, ULRICH;CROASDALE, REBECCA;DILL, SIMONE;DORMEYER, WILMA;GEORGES, GUY;GROTE, MICHAEL;HAAS, ALEXANDER;HOFFMANN, EIKE;ICKENSTEIN, LUDGER MARKUS;JAHN-HOFMANN, KERSTIN;JOHN, MATTHIAS;METZ, SILKE;MUNDIGL, OLAF;SCHEUER, WERNER;STRACKE, JAN OLAF
分类号 A61K39/395;A61K47/48;C07K16/16;C07K16/28;C07K16/32;C07K16/44;C07K16/46;C12N15/113 主分类号 A61K39/395
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