发明名称 METHOD FOR DETERMINING CHEMOTHERAPEUTIC REGIMEN BASED ON ERCC1 AND TS EXPRESSION
摘要 PROBLEM TO BE SOLVED: To provide a prognostic method useful in medicine, particularly cancer chemotherapy.SOLUTION: A method for evaluating TS and/or ERCC1 expression levels in immobilized or immobilized and paraffin embedded tissues is provided. Estimation of probable resistance of the tumor of a patient to be treated by 5-FU and oxaliplatin-based therapies by examining the amount of TS and/or ERCC1 mRNA in tumor cells of the patient and comparing the amount to a predetermined threshold expression level for those genes is also provided.
申请公布号 JP2011004756(A) 申请公布日期 2011.01.13
申请号 JP20100177164 申请日期 2010.08.06
申请人 RESPONSE GENETICS INC 发明人 DANENBERG KATHLEEN D
分类号 C12N15/09;C12Q1/68;A61K31/282;A61K31/513;A61P35/00;A61P43/00;C12P19/34;C12Q;G01N33/50;G01N33/574 主分类号 C12N15/09
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