发明名称 |
NANOSCALE PLATINUM COMPOUNDS AND METHODS OF USE THEREOF |
摘要 |
The invention is directed to biocompatible conjugated polymer nanoparticles including a copolymer backbone, a plurality of sidechains covalently linked to said backbone, and a plurality of platinum compounds dissociably linked to said backbone. The invention is also directed to dicarbonyl-lipid compounds wherein a platinum compound is dissociably linked to the dicarbonyl compound. The invention is also directed to methods of treating cancer or metastasis. The methods includes selecting a subject in need of treatment for cancer or metastasis and administering to the subject an effective amount of any of the nanoparticles, compounds, or compositions of the invention. |
申请公布号 |
HK1167869(A1) |
申请公布日期 |
2016.07.22 |
申请号 |
HK20120108633 |
申请日期 |
2012.09.04 |
申请人 |
THE BRIGHAM AND WOMENS HOSPITAL INC. |
发明人 |
SENGUPTA, Shiladitya;PARASKAR, Abhimanyu;SONI, Shivani;BASU, Sudipta;SENGUPTA, Poulomi |
分类号 |
C08F;A61K;A61P |
主分类号 |
C08F |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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