| 摘要 |
PROBLEM TO BE SOLVED: To provide methods of using Bv8 and EG-VEGF polypeptides and nucleic acids to promote hematopoiesis, methods of screening for modulators of Bv8 and EG-VEGF activity, and methods of treatment using Bv8 and EG-VEGF polypeptides or Bv8 and EG-VEGF antagonists.SOLUTION: A method for inducing proliferation of bone-marrow cells and their progeny includes contacting the cells with Bv8. A method of treating a mammal for a condition associated with abnormal hematopoiesis includes administering to the mammal Bv8 antagonists, EG-VEGF antagonists, or combinations thereof. |
