发明名称 |
AZABICYCLO COMPOUND AND SALT THEREOF |
摘要 |
<p>Disclosed is a novel azabicyclo compound which has both HSP90 inhibitory activity and cell proliferation inhibitory effect. Specifically disclosed is a compound represented by general formula (I) or a salt thereof. (In the formula, X1 represents CH or N; one of X2, X3 and X4 represents N, and the others respectively represent CH; one or two of Y1, Y2, Y3 and Y4 respectively represent C-R4, and the others may be the same or different and respectively represent CH or N; R1 represents an optionally substituted monocyclic or bicyclic unsaturated heterocyclic group that has 1-4 heteroatoms selected from among N, S and O; R2 represents an alkyl group having 1-6 carbon atoms, or the like; and R3 and R4 respectively represent -CO-R5 or the like.)</p> |
申请公布号 |
CA2767556(A1) |
申请公布日期 |
2011.01.13 |
申请号 |
CA20102767556 |
申请日期 |
2010.07.09 |
申请人 |
TAIHO PHARMACEUTICAL CO., LTD. |
发明人 |
KITADE, MAKOTO;OHKUBO, SHUICHI;YOSHIMURA, CHIHOKO;YAMASHITA, SATOSHI;OSHIUMI, HIROMI;UNO, TAKAO;KAWAI, YUICHI |
分类号 |
C07D471/04;A61K31/437;A61K31/444;A61K31/4709;A61K31/5377;A61P35/00;A61P35/02;A61P43/00;C07D519/00 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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