METHODS AND COMPOSITIONS FOR INCREASED SAFETY OF STEM CELL-DERIVED POPULATIONS
摘要
The invention provides methods and compositions relating to differentiated cell populations that derive from pluripotent stem cells. The methods relate to reducing the number of residual stem cells present in such populations. The compositions include differentiated cell populations that contain reduced number of stem cells or that contain no stem cells. Pluripotent stem cells may be reduced in number and/or function through exposure to low oxygen levels.
申请公布号
WO2011005326(A1)
申请公布日期
2011.01.13
申请号
WO2010US01934
申请日期
2010.07.09
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;COLTON, CLARK, K.;MILLMAN, JEFFREY, R.