发明名称 STABLE FORMULATIONS OF THIADIAZOLE DERIVATIVE
摘要 The present invention provides formulation parameters and manufacturing conditions for stable pharmaceutical compositions comprising N-{4-(2,2-dimethyl-propionyl)-(5R)-5-[(2-ethylamino-ethanesulfonylamino)-methyl]-5-phenyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl}-2,2-dimethyl-propionamide that minimize undesirable chiral conversion to the less active S enantiomeric form.
申请公布号 US2011009458(A1) 申请公布日期 2011.01.13
申请号 US20080665740 申请日期 2008.07.07
申请人 ELI LILLY AND COMPANY;KYOWA HAKKO KIRIN CO., LTD. 发明人 KUSANO HIROKO;MISHRA DINESH SHYAMDEO;TASHIRO YOSHIKAZU;WATANABE YOSUKE;ZHUANG HONG
分类号 A61K31/433;A61P35/00 主分类号 A61K31/433
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