发明名称 |
METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF MACROMOLECULES |
摘要 |
The invention provides compositions and methods that enhance the delivery of large macromolecules (i.e., greater than 10kDa), such as antigen-binding polypeptides, across tight junctions. Such methods and compositions are particularly useful for delivering therapeutic antigen-binding polypeptides to the CNS, via intranasal administration, for the treatment of neurological disorders. |
申请公布号 |
WO2010003268(A3) |
申请公布日期 |
2011.01.13 |
申请号 |
WO2009CH00248 |
申请日期 |
2009.07.10 |
申请人 |
ESBATECH, AN ALCON BIOMEDICAL RESEARCH UNIT LLC;HULMANN-COTTIER, VALERIE;URECH, DAVID;FURRER, ESTHER |
发明人 |
HULMANN-COTTIER, VALERIE;URECH, DAVID;FURRER, ESTHER |
分类号 |
A61K9/08;A61K39/00;A61K47/36 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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