| 发明名称 |
METHODS RELATED TO A MUTATION IN COMPLEMENT FACTOR H-RELATED PROTEIN 5 IN PATIENTS WITH GLOMERULONEPHRITIS |
| 摘要 |
The invention relates to methods of regulating complement. In particular, the inventors have identified a relationship between a particular gene, CFHR5, and irregularities in complement regulation. The invention provides a method for diagnosing a complement related disease, comprising identifying a mutation in the CFHR5 gene in a sample obtained from a subject. |
| 申请公布号 |
WO2011004148(A1) |
申请公布日期 |
2011.01.13 |
| 申请号 |
WO2010GB01295 |
申请日期 |
2010.07.06 |
| 申请人 |
UCL BUSINESS PLC;GALE, DANIEL;MAXWELL, PATRICK;PICKERING, MATTHEW;GOICOECHEA DE JORGE, ELENA |
发明人 |
GALE, DANIEL;MAXWELL, PATRICK;PICKERING, MATTHEW;GOICOECHEA DE JORGE, ELENA |
| 分类号 |
C07K14/47;A01K67/027;A61K38/00;A61P13/12;C12Q1/68;G01N33/50;G01N33/564 |
主分类号 |
C07K14/47 |
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