发明名称 |
SCREENING METHOD OF THERAPEUTIC AND DIAGNOSTIC AGENTS FOR TNF-ALPHA-INDUCED DISEASES USING REACTIVE OXYGEN SPECIES MODULATOR 1 |
摘要 |
Disclosed are methods for screening therapeutics, prophylactics or pain alleviators for diseases induced by TNF-a, a main mediator of inflammation and in ROS production and cell death, and for diagnosing the diseases, and a diagnostic kit. For this, a nucleotide sequence and an amino acid sequence of Romo1, which plays an important role in the ROS production and cell death pathway of TNF-a signaling are utilized. |
申请公布号 |
WO2011004949(A1) |
申请公布日期 |
2011.01.13 |
申请号 |
WO2010KR00141 |
申请日期 |
2010.01.11 |
申请人 |
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION;YOO, YOUNG-DO;KIM, JUNG-JIN |
发明人 |
YOO, YOUNG-DO;KIM, JUNG-JIN |
分类号 |
C12Q1/68;G01N33/15 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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地址 |
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