| 摘要 |
PROBLEM TO BE SOLVED: To provide a granular pharmaceutical composition comprising medicine having unpleasant taste, wax-like material and sugar alcohol.SOLUTION: The granular pharmaceutical composition for oral administration is obtained by: heating and melting one or more wax-like substances selected from among (b) hardened oil, vegetable fat and oil, animal fat and oil, polyethylene glycol, stearic acid, glycerol fatty acid ester and sucrose fatty acid ester; dispersing or dissolving the (a) drug having the unpleasant taste into this so that a weight ratio of the (a) to the (b) is 1:1 to 1:5; and mixing or secondarily granulating the (c) sugar alcohol to a primary granule to be obtained by granulation. |
