发明名称 |
BINDING AGENTS DIRECTED AGAINST IL-4 RECEPTOR FOR THE TREATMENT OF TUMORS, INFLAMMATORY AND IMMUNOLOGICAL DISORDERS |
摘要 |
The present invention relates to the use of an antigen-binding agent directed against human interleukin-4 receptor for the prevention and/or treatment of tumors, inflammatory and immunological disorders. Further the invention relates to methods of inhibiting the bioactivity of IL-4 without inhibiting binding of IL-4 to IL-4R and particularly to methods for treatment and/or prevention of tumors, inflammatory and immunological disorders, the methods comprising administering to an individual in need thereof an antigen-binding agent with binding affinity for IL-4R.
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申请公布号 |
US2011008326(A1) |
申请公布日期 |
2011.01.13 |
申请号 |
US20090922433 |
申请日期 |
2009.03.30 |
申请人 |
HILL OLIVER;BRANSCHAEDEL MARCUS;GIEFFERS CHRISTIAN;THIEMANN MEINOLF;MERZ CHRISTIAN |
发明人 |
HILL OLIVER;BRANSCHAEDEL MARCUS;GIEFFERS CHRISTIAN;THIEMANN MEINOLF;MERZ CHRISTIAN |
分类号 |
A61K39/395;A61P11/06;A61P17/00;A61P19/02;A61P29/00;A61P31/06;A61P35/00;A61P37/00;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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