| 发明名称 |
CRYSTALLISATION PROCESS FOR 1-(.BETA.-D-GLUCOPYRANOSYL)-4-METHYL-3-[5-(4-FLUOROPHENYL)-2-THIENYLMETHYL] BENZENE |
| 摘要 |
The present invention relates to a crystallisation procedure to obtain 1 -(ß-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl] benzene hemihydrate crystals having a narrow particle size distribution and improved flowability, bulk and tap density properties. |
| 申请公布号 |
CA2767258(A1) |
申请公布日期 |
2011.01.13 |
| 申请号 |
CA20102767258 |
申请日期 |
2010.07.08 |
| 申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
RAMMELOO, THOMAS JOACHIM LANDEWALD;DE KEYSER, RUBEN;SCHILDERMANS, GUSTAAF JOZEF PETRUS |
| 分类号 |
C07D309/10 |
主分类号 |
C07D309/10 |
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