Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.
申请公布号
HK1215670(A1)
申请公布日期
2016.09.09
申请号
HK20160103611
申请日期
2016.03.30
申请人
AVEO Pharmaceuticals Inc.
发明人
LERNER, Lorena L;ABBOTT, Sandra S;BAI, Ailin A;CHEN, Ting;CHIU, Maria, Isabel M I;LIU, Qing Q;POLING, Laura L;TAO, Nianjun N;WEILER, Solly S;WENG, Zhigang;WINSTON, William, M. W M;GYURIS, Jeno J
