摘要 |
<p>Disclosed are a novel thiazole-containing benzophenone derivative represented by formula 1, and an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof and a solvate thereof, a pharmaceutical composition comprising the derivative, a use of the derivative as therapeutic agent and a method for preparing the derivative. The benzophenone thiazole derivatives inhibit formation of microtubules and eliminate actively proliferating cells of malignant tumors to control general cell proliferation. In formula 1, R, R 1 and R 2 are defined as above.</p> |
申请人 |
CHONG KUN DANG PHARMACEUTICAL CORP. |
发明人 |
CHOI, NAM-SONG;KIM, YOUNG-HOON;LEE, JAE-KWANG;KANG, HEE-RYONG;CHOI, HO-JIN;MOON, SEUNG-KEE;KIM, SOO-JIN;PARK, GYU-TAE;HAN, BYEONG-HOON;KIM, DAL-HYUN;CHOI, JAE-HOON;LEE, SUNG-SOOK;AHN, SOON-KIL;LEE, KYUNG-JOO;BAE, SU-YEAL |