发明名称 |
FIVE-MEMBERED RING COMPOUND |
摘要 |
<p>Provided are: a five-membered ring compound represented by formula (1) or a pharmaceutically acceptable salt thereof and a medicine containing the compound or salt. The compound or salt inhibits the infiltration of leukocytes such as eosinophils and lymphocytes, is effective as a therapeutic agent for various kinds of inflammation, and is so safe that the compound or salt can be taken for long. In formula (1), R 1 is (substituted) phenyl or pyridyl; R 2 is (substituted) pyrazinediyl, pyrimidinediyl, or pyridazinediyl; R 3 to R 5 each is alkyl (provided that -N(R 4 )R 5 may be morpholino); and Y 2 is alkylene.</p> |
申请公布号 |
EP2272844(A1) |
申请公布日期 |
2011.01.12 |
申请号 |
EP20090735351 |
申请日期 |
2009.04.23 |
申请人 |
DAINIPPON SUMITOMO PHARMA CO., LTD. |
发明人 |
FUJITA, HITOSHI;IKEDA, JUNYA;IMAI, SATOKI |
分类号 |
A61P3/10;C07D417/04;A61K31/501;A61K31/5377;A61P1/04;A61P9/00;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/04;A61P19/02;A61P25/00;A61P27/02;A61P29/00;A61P35/04;A61P37/02;A61P37/08;A61P43/00;C07D417/14 |
主分类号 |
A61P3/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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