发明名称 |
NEW MANDELIC ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS |
摘要 |
There is provided a compound of formula (I) and pharmaceutically-acceptable derivatives (including prodrugs) thereof, which compound and derivatives are useful as, or are useful as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
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申请公布号 |
CA2456426(C) |
申请公布日期 |
2011.01.11 |
申请号 |
CA20022456426 |
申请日期 |
2002.08.30 |
申请人 |
ASTRAZENECA AB |
发明人 |
INGHARDT, TORD;JOHANSSON, ANDERS;SVENSSON, ARNE |
分类号 |
C07D205/04;A61K31/397;A61P7/02;C07C45/00;C07C45/29;C07C45/51;C07C45/67;C07C45/71;C07C47/575;C07C59/56;C07C59/64;C07C69/732;C07C69/734;C07C69/738;C07C205/59;C07D207/16;C07D213/34;C07D213/54;C07D239/28;C07D261/08;C07D401/12;C07D403/12;C07D413/12 |
主分类号 |
C07D205/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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