发明名称 |
Polypeptide carrier protein |
摘要 |
The invention relates to polypeptide carrier proteins that comprise at least five CD4+ T cell epitopes, for conjugation to capsular polysaccharides. The carrier proteins are useful as components of vaccines that can elicit a T-cell dependent immune response. These vaccines are particularly useful to confer protection against infection from encapsulated bacteria in infants between the ages of 3 months and about 2 years.
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申请公布号 |
US7867498(B2) |
申请公布日期 |
2011.01.11 |
申请号 |
US20090383545 |
申请日期 |
2009.03.25 |
申请人 |
NOVARTIS AG |
发明人 |
RAPPUOLI RINO;GRANDI GUIDO |
分类号 |
A01K67/027;A61K39/00;A61K38/00;A61K39/015;A61K39/02;A61K39/08;A61K39/095;A61K39/10;A61K39/116;A61K39/12;A61K39/29;A61K39/295;A61K39/38;A61K45/00;A61K47/48;A61P31/04;C07K14/00;C07K14/02;C07K14/11;C07K14/22;C07K14/235;C07K14/33;C07K14/34;C07K14/445;C07K19/00;C12N1/21;C12N5/10;C12N15/09;C12P21/02;C12R1/19 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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