发明名称 MEMBRANE FUSION INHIBITOR
摘要 The present invention provides a pharmaceutical composition that has excellent safety and targets a different step in the virus propagation cycle than conventional pharmaceutical compositions, applicable as an antiviral agent. A pharmaceutical composition containing an epigallocatechin gallate derivative represented by the following chemical formula (1), an isomer thereof, or a salt thereof is prepared. This can be used as a membrane fusion inhibitor that inhibits viral membrane fusion. In the following formula, R1 to R6 are each a hydrogen atom, halogen, sodium, potassium, or a straight-chain or branched, saturated or unsaturated acyl group and may be identical to or different from one another. The acyl group may be substituted further with one or more substituents. At least one of R1 to R6 is the acyl group. R7 to R16 are each a hydrogen atom, halogen, sodium, or potassium and may be identical to or different from one another.
申请公布号 US2011003889(A1) 申请公布日期 2011.01.06
申请号 US20090865360 申请日期 2009.02.02
申请人 KAIHATSU KUNIHIRO;MORI SHUICHI;DAIDOJI TOMO;KATO NOBUO;MIYAKE SHINYA 发明人 KAIHATSU KUNIHIRO;MORI SHUICHI;DAIDOJI TOMO;KATO NOBUO;MIYAKE SHINYA
分类号 A61K31/353;A61P31/12;C07D311/62 主分类号 A61K31/353
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