<p>We describe a method to determine effectiveness of a compound or composition in treatment of celiac disease or gluten intolerance, the method comprising: - administration of the compound or composition to one or more human patients who were on a gluten-free diet for 10 years or less, preferably 6 years or less; - challenge with gluten of the one or more human patients who were administered the compound or composition; and - determining whether there is a change in condition of celiac disease or gluten intolerance of the one or more patients that results from administration of the compound or composition and challenge with gluten; whereby no significant change in condition indicates that the compound or composition would be effective in treating celiac disease or gluten intolerance.</p>
申请公布号
WO2011000773(A1)
申请公布日期
2011.01.06
申请号
WO2010EP58997
申请日期
2010.06.24
申请人
DSM IP ASSETS B.V.;BRUINS, MAAIKE, JOHANNA;EDENS, LUPPO