| 发明名称 |
METHOD OF MAKING HYBRID CELLS THAT EXPRESS USEFUL ANTIBODIES |
| 摘要 |
This invention relates to a novel hybridoma strategy that uses CD27+ B cells cultured in vitro to induce IgM to IgG class switch prior to fusion with a fusion partner. Hybridomas resulting from the fusion between CD27+ B cells and a fusion partner cell line and antibodies secreted from the hybridomas are included in the invention.
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| 申请公布号 |
US2011002937(A1) |
申请公布日期 |
2011.01.06 |
| 申请号 |
US20090864889 |
申请日期 |
2009.01.28 |
| 申请人 |
THOMAS JEFFERSON UNIVERSITY |
发明人 |
DESSAIN SCOTT K.;ADEKAR SHARAD P. |
| 分类号 |
A61K39/40;A61P25/00;A61P31/04;C07H21/00;C07K16/00;C12N5/12;C12P21/08;C40B40/10;C40B50/06 |
主分类号 |
A61K39/40 |
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