发明名称 |
METHODS AND KITS FOR HIGH EFFICIENCY ENGINEERING OF CONDITIONAL MOUSE ALLELES |
摘要 |
The present invention concerns methods and kits for the direct, targeted engineering of conditional alleles in rodent embryonic stem cells in which the conditional allele is replaced with a DNA of interest without first introducing heterotypic recombination sites, thus providing high efficiency targeted exchange of genetic material. |
申请公布号 |
WO2011001247(A2) |
申请公布日期 |
2011.01.06 |
申请号 |
WO2010IB01560 |
申请日期 |
2010.06.28 |
申请人 |
UNIVERSITY OF BASEL;LOPEZ-RIOS, JAVIER;ZELLER. ROLF;OSTERWALDER, MARCO |
发明人 |
LOPEZ-RIOS, JAVIER;ZELLER. ROLF;OSTERWALDER, MARCO |
分类号 |
C12N15/90 |
主分类号 |
C12N15/90 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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