发明名称 |
METHOD FOR PRODUCING A CELL CAPABLE OF HIGH-YIELD PRODUCTION OF HETEROPROTEINS |
摘要 |
The present invention provides a cell capable of high-yield production of polypeptides and a method for producing the same. The present invention relates to a method for producing a cell capable of high-yield production of a desired polypeptide, wherein a strongly taurine transporter-expressing cell into which DNA encoding the desired polypeptide has been introduced is cultured in the presence of a high concentration of methotrexate and a cell capable of high-yield production of the desired polypeptide is selected from among surviving cells.
|
申请公布号 |
US2011003334(A1) |
申请公布日期 |
2011.01.06 |
申请号 |
US20080733815 |
申请日期 |
2008.10.14 |
申请人 |
TABUCHI HISAHIRO;SUGIYAMA TOMOYA |
发明人 |
TABUCHI HISAHIRO;SUGIYAMA TOMOYA |
分类号 |
C12P21/08;C12N5/10;C12P21/00 |
主分类号 |
C12P21/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|