摘要 |
<p>The present invention relates to a method for the assessment of a biological sample, comprising the steps of (a) obtaining a UV radiation reaction image of a biological sample; (b) establishing at least one of the following parameters: the size of a cell, the morphology of a cell, the number of cells, the ratio between cytoplasm and nucleus of a cell and the optical density of the nucleus of a cell present on said UV radiation reaction image; and (c) determining the percentage of epithelial cells present on said UV radiation reaction image based on the outcome of step (b). The present invention is especially suited for the assessment of squamous or glandular cells and particularly relates to the analysis of biological smear samples, e.g. cervical smear samples. In a further aspect the present invention relates to a device comprising a means for obtaining a UV radiation reaction image, a means for establishing the size of a cell, the morphology of a cell, the shape of a cell, the number of cells, the ratio between cytoplasm and nucleus of a cell and the optical density of the nucleus of a cell present on said UV radiation reaction image; and a means for determining the percentage of epithelial cells of cells present on said UV radiation reaction image, as well as a use of such a device for the assessment of a biological sample.</p> |