| 摘要 |
<p>Disclosed are a cell selection apparatus and a cell selection method for selecting a mass of cells capable of producing a specific substance, all at once easily in a short period of time, and further, for efficiently selecting these cells based on the strength of a binding force between the specific substance on the surface of the cell and a recognition molecule. The cell selection apparatus includes: a cell selection vessel which has a pair of electrodes and a sheet-like insulating material having a plurality of micropores, with a recognition molecule bindable to the specific substance being disposed on a bottom face of the micropore; and a power supply, wherein the power supply includes a cell-immobilization power supply and a cell-taking power supply. The cell selection method uses the cell selection apparatus, including; introducing cells into a cell selection area; immobilizing these cells in the micropores; effecting a binding reaction between the specific substance on the surface of the cell and the recognition molecule; thereafter, taking out a cell of which the specific substance on the surface of the cell is not or is weakly bound to the recognition molecule, among the entire population of the cells, from the micropore; otherwise alternatively, leaving a cell of which the specific substance on the surface of the cell is strongly bound to the recognition molecule, among the entire population of the cells, behind in the micropore.</p> |
